abstract：:Cosmeceuticals are understood to be active cosmetics that are sold over-the-counter, but have profound effects on skin appearance and functioning. This term has no legal meaning in the United States, because only cosmetics and pharmaceuticals are recognized by regulatory bodies. Cosmeceuticals are carefully developed ...

journal_title：Dermatologic clinics

authors： Draelos ZD

更新日期：2014-04-01 00:00:00

abstract：:Understanding the anatomy and distribution of facial fat and the alterations that occur during the aging process is essential to effectively and precisely achieve facial rejuvenation. Over the past several years, through cadaveric dissections and computed tomographic studies, much has been discovered concerning the ad...

journal_title：Dermatologic clinics

authors： Fitzgerald R,Rubin AG

更新日期：2014-01-01 00:00:00

abstract：:The anatomic region influences the dermoscopic features of different lesions. In this article, the particular characteristics of the scalp, mucosal membranes, and lesions located on the milk line are explained. In histopathology, the benign melanocytic lesions in these locations are also named nevi of special sites, c...

journal_title：Dermatologic clinics

authors： Hofmann-Wellenhof R

更新日期：2013-10-01 00:00:00

abstract：:Autoinflammatory diseases (AIDs) are characterized by recurrent episodes of systemic and organ-specific inflammation. Many of these diseases share fever as a common presenting feature. Physicians need to consider AIDs in children with recurrent, unexplained fevers, when infectious and malignant causes have been discar...

journal_title：Dermatologic clinics

authors： Hausmann JS,Dedeoglu F

更新日期：2013-07-01 00:00:00

abstract：:Due to many factors, including parental anxiety, a child's inability to understand the necessity of a procedure and a child's unwillingness to cooperate, it can be much more challenging to perform dermatologic procedures in children. This article reviews pre-procedural preparation of patients and parents, techniques f...

journal_title：Dermatologic clinics

authors： Metz BJ

更新日期：2013-04-01 00:00:00

abstract：:Skin disease is highly prevalent in the United States, and it has been well-documented that patients with skin disease experience financial, psychological, social, and quality-of-life (QoL) burdens beyond those of the general population. Pediatric patients and their caregivers are particularly vulnerable to the burden...

journal_title：Dermatologic clinics

authors： Brown MM,Chamlin SL,Smidt AC

更新日期：2013-04-01 00:00:00

abstract：:Alopecia areata (AA) is a recurrent autoimmune type of hair loss that affects about 5.3 million people in the United States alone. Despite being the most prevalent autoimmune disease, the molecular and cellular mechanisms underlying this complex disease are still poorly understood, and rational treatments are lacking....

journal_title：Dermatologic clinics

authors： Jabbari A,Petukhova L,Cabral RM,Clynes R,Christiano AM

更新日期：2013-01-01 00:00:00

abstract：:Dermatopathology (DP) education is critical to the comprehensive training of dermatology and pathology residents and to the accurate diagnosis and management of cutaneous disease. DP has seen tremendous growth, and its success depends on our ability to effectively educate future leaders, teachers, and researchers who ...

journal_title：Dermatologic clinics

authors： Hinshaw MA

更新日期：2012-10-01 00:00:00

abstract：:This article reviews the recent dermatopathology literature involving nonmelanocytic neoplasia, with a focus on important work done over the last 5 years. The discussion includes advances in the understanding of Merkel cell carcinoma pathogenesis and prognosis; changes in the seventh edition of the American Joint Comm...

journal_title：Dermatologic clinics

authors： Sidhu HK,Patel RV,Goldenberg G

更新日期：2012-10-01 00:00:00

abstract：:Although new technologies are becoming available to aid in diagnosis, the skin biopsy continues to be the fundamental tool of the dermatologist to evaluate the nature of a pigmented lesion. There are 3 major techniques for the biopsy of a pigmented lesion: shave biopsy, punch/incisional biopsy, and excisional biopsy. ...

journal_title：Dermatologic clinics

authors： Silverstein D,Mariwalla K

更新日期：2012-07-01 00:00:00

abstract：:Vitiligo, an acquired disease of depigmentation, affects millions worldwide. The psychosocial and health-related quality of life (HRQL) impact of the disease varies based on several parameters, including country of origin, skin type, gender, age, marital status, and involved body site. Many instruments, both dermatolo...

journal_title：Dermatologic clinics

authors： Bhandarkar SS,Kundu RV

更新日期：2012-04-01 00:00:00

abstract：:Contact dermatitis in the United States poses a significant public health concern. This article provides a definition of contact dermatitis and its associated risk factors. The authors discuss the epidemiology of occupational contact dermatitis including its incidence and prevalence, and describe how estimates are cal...

journal_title：Dermatologic clinics

authors： Cashman MW,Reutemann PA,Ehrlich A

更新日期：2012-01-01 00:00:00

abstract：:The exact epidemiology of autoimmune bullous disorders in Australia is unknown. This article describes the establishment of a registry and support group to serve patients with these disorders. The registry aids research in Australia by providing epidemiologic data and maintaining an up-to-date database with patient co...

journal_title：Dermatologic clinics

authors： Daniel BS,Dermawan A,Murrell DF

更新日期：2011-10-01 00:00:00

abstract：:The therapeutic approach to mucous membrane pemphigoid is site specific, with the goal of preserving function for patients with chronic and treatment-resistant disease. The involvement of certain mucosal sites (ie, ocular, laryngeal, esophageal, nasopharyngeal, and anogenital) is high risk and warrants more aggressive...

journal_title：Dermatologic clinics

authors： Kourosh AS,Yancey KB

更新日期：2011-10-01 00:00:00

abstract：:Rituximab is a chimeric, murine-human, monoclonal antibody against the CD20 antigen of B lymphocytes. It has been used off-label to treat and manage autoimmune and dermatologic diseases as an alternative or adjuvant therapy to systemic treatments. Due to cost, potential complications, and lack of data rituximab is use...

journal_title：Dermatologic clinics

authors： Daniel BS,Murrell DF,Joly P

更新日期：2011-10-01 00:00:00

abstract：:Objectively evaluating disease activity in autoimmune bullous disease (AIBD) is important in terms of the clinical assessment of patients and as an outcome measure for clinical trials. Measures need to be general enough to capture the issues specific to each of the bullous dermatoses but specific enough to capture any...

journal_title：Dermatologic clinics

authors： Sebaratnam DF,Murrell DF

更新日期：2011-07-01 00:00:00

abstract：:Pemphigoid gestationis is a rare, autoimmune bullous disease of pregnancy that involves autoantibodies directed against type XVII collagen in the basement membrane zone. This article discusses the immunopathogenesis, diagnostic methods, and clinical features of this fascinating disease. ...

journal_title：Dermatologic clinics

authors： Intong LR,Murrell DF

更新日期：2011-07-01 00:00:00

abstract：:The success of the Mohs procedure depends on the reliability of each step in the technique. Pitfalls in histologic preparation of the tissue specimens may occur during debulking, excising, orienting, creating the map, sectioning, inking, tissue flattening and freezing, cutting, slide fixation, staining, and mapping th...

journal_title：Dermatologic clinics

authors： Bouzari N,Olbricht S

更新日期：2011-04-01 00:00:00

abstract：:This article provides a protocol for the systematic approach to the technique of Mohs micrographic surgery. Each step, from tumor excision and tissue mapping, to specimen processing and histologic interpretation, through wound closure and postoperative management, is covered. The advantages of Mohs surgery over other ...

journal_title：Dermatologic clinics

authors： Benedetto PX,Poblete-Lopez C

更新日期：2011-04-01 00:00:00

abstract：:The term pyoderma encompasses a variety of distinct entities including impetigo (bullous and nonbullous), erysipelas, cellulitis, folliculitis, and staphylococcal scalded skin syndrome. Treatment of pyodermas centers around wound care and appropriate antibiotic selection. Triphenylmethane dyes, such as gentian violet,...

journal_title：Dermatologic clinics

authors： Berrios RL,Arbiser JL

更新日期：2011-01-01 00:00:00

abstract：:Hidradenitis suppurativa (HS) is a chronic, inflammatory, scarring condition involving the intertriginous skin of the axillary, inguinal, inframammary, genital, and perineal areas of the body. It is also referred to as acne inversa and Verneuil disease. Follicular occlusion is the primary event in HS. It is now accept...

journal_title：Dermatologic clinics

authors： Danby FW,Margesson LJ

更新日期：2010-10-01 00:00:00

abstract：:Patients with urogenital complaints are frequently encountered by family practitioners, gynecologists, and dermatologists. This review article provides practical information regarding normal anatomy and embryology of the vulva, followed by a summary of procedural techniques. The new classifications of vulvar inflammat...

journal_title：Dermatologic clinics

authors： Selim MA,Hoang MP

更新日期：2010-10-01 00:00:00

abstract：:Although clinical trials for new drugs are often limited in children because of safety concerns or restrictions, new therapies or novel strategies with old drugs have recently expanded dermatologic armamentarium for pediatric patients. Oral propranolol is currently the first choice in the treatment of alarming infanti...

journal_title：Dermatologic clinics

authors： Gelmetti C,Frasin A,Restano L

更新日期：2010-07-01 00:00:00

abstract：:Cutaneous T-cell lymphoma is a malignancy of skin-homing T cells. This unique population of lymphocytes requires alternative therapies to those used in nodal lymphomas. Although phototherapy and nitrogen mustard have been standard treatments for decades, newer therapies have been arriving with increased frequency. Mor...

journal_title：Dermatologic clinics

authors： Poligone B,Heald P

更新日期：2010-07-01 00:00:00

abstract：:The Israeli population is characterized by unique demographic features including high genetic homogeneity within many closed communities. As a consequence the molecular epidemiology of epidermolysis bullosa differs markedly in this country and surrounding areas from that reported in the Western world. ...

journal_title：Dermatologic clinics

authors： Sprecher E

更新日期：2010-04-01 00:00:00

abstract：:Epidermolysis bullosa (EB) in Mexico continues to be a rare genodermatosis that is still unknown for most of the health care professionals in the country. The spirit of DebRA MEXICO was born in 1994 when the Mexican health care team started to see patients with the main purpose to provide medical care, genetic counsel...

journal_title：Dermatologic clinics

authors： Liy-Wong C,Cepeda-Valdes R,Salas-Alanis JC

更新日期：2010-04-01 00:00:00

abstract：:Involvement of the genitourinary tract has been described in many different types of epidermolysis bullosa (EB). Pathology may be broadly divided into problems resulting in obstruction, that may in turn lead to hydroureter or hydronephrosis, or disease primarily affecting the renal parenchyma. Left unrecognized and un...

journal_title：Dermatologic clinics

authors： Almaani N,Mellerio JE

更新日期：2010-04-01 00:00:00

abstract：:In all forms of epidermolysis bullosa (EB), skin fragility may result in bacterial colonization or infection, particularly in the more severe forms where wounds may be multiple and long-standing. A balance exists between a wound's bacterial load and the host defenses, such that there is a spectrum from simple contamin...

journal_title：Dermatologic clinics

authors： Mellerio JE

更新日期：2010-04-01 00:00:00

abstract：:The craniofacial and oral manifestations of the different epidermolysis bullosa (EB) types vary markedly in character and severity depending largely on the EB type. The tissues affected and the phenotypes displayed are closely related to the specific abnormal or absent proteins resulting from the causative genetic mut...

journal_title：Dermatologic clinics

authors： Wright JT

更新日期：2010-01-01 00:00:00

abstract：:Laryngo-onycho-cutaneous (LOC) syndrome was reclassified as a subtype of junctional epidermolysis bullosa (JEB) based on clinical features similar to JEB and its association, in the majority of patients from the Punjab, with a unique mutation affecting the N terminus of the alpha3 chain of LM332. Although LOC syndrome...

journal_title：Dermatologic clinics

authors： Cohn HI,Murrell DF

更新日期：2010-01-01 00:00:00

abstract：:Current aesthetic dermatology rejuvenation options offer minimally invasive, more affordable alternatives to traditional cosmetic surgery. Chemical peels and laser resurfacing can significantly improve the appearance of the skin and stimulate neocollagenesis; botulinum toxin reduces the appearance of dynamic facial li...

journal_title：Dermatologic clinics

authors： Hirsch R,Stier M

更新日期：2009-10-01 00:00:00

abstract：:Cosmeceuticals are topically applied products that are more than merely cosmetic, yet are not true drugs that have undergone rigorous placebo controlled studies for safety and efficacy. There are many review articles that outline the theoretical biologic and clinical actions of these cosmeceuticals and their various i...

journal_title：Dermatologic clinics

authors： Reszko AE,Berson D,Lupo MP

更新日期：2009-10-01 00:00:00

abstract：:Contact dermatitis is the most common occupational skin disorder, responsible for up to 30% of all cases of occupational disease in industrialized nations. Epidemiologic data suggest that contact dermatitis accounts for 90% to 95% of all cases of occupational skin disease, imposing considerable social and economic imp...

journal_title：Dermatologic clinics

authors： Clark SC,Zirwas MJ

更新日期：2009-07-01 00:00:00

abstract：:Hand dermatitis is a common disease of the skin resulting in significantly decreased quality of life. Allergic contact dermatitis is a frequent cause of hand dermatitis. Recent studies have revealed that biocides used as preservatives are frequent allergens affecting the hands. This article reviews common biocides imp...

journal_title：Dermatologic clinics

authors： Maier LE,Lampel HP,Bhutani T,Jacob SE

更新日期：2009-07-01 00:00:00

abstract：:In this article, the authors summarize the published literature on the reliability and accuracy of teledermatology. The first section reports on the diagnostic reliability of teledermatology compared with face-to-face clinic consultation. In the second section, the authors report on the "intragroup" diagnostic agreeme...

journal_title：Dermatologic clinics

authors： Levin YS,Warshaw EM

更新日期：2009-04-01 00:00:00

abstract：:Dermatologists can decrease unnecessary use of antimicrobial agents by avoiding them in situations wherein good evidence indicates that they are ineffective. Controlled trials indicate that antimicrobial agents are unhelpful in treating cutaneous abscesses, inflamed epidermal cysts, uninfected atopic eczema, and cutan...

journal_title：Dermatologic clinics

authors： Hirschmann JV

更新日期：2009-01-01 00:00:00

abstract：:Calciphylaxis is defined by the presence of calcium deposits within the wall of small and medium-sized vessels. It is classically considered a life-threatening disease in patients with end-stage renal disease under dialysis. Clinically, it is characterized by the presence of painful plaques surrounded by a reticulate ...

journal_title：Dermatologic clinics

authors： Daudén E,Oñate MJ

更新日期：2008-10-01 00:00:00

abstract：:Traumatic panniculitis refers to changes in the subcutaneous fat related to physical or chemical agents. The clinical picture of traumatic panniculitis is nonspecific. Cutaneous lesions are indurated, warm, red, subcutaneous plaques or nodules not necessary related to the intensity of the injury. The histologic pictur...

journal_title：Dermatologic clinics

authors： Moreno A,Marcoval J,Peyri J

更新日期：2008-10-01 00:00:00

abstract：:Medical spas are the fasting growing segment of the 15-billion dollar spa industry. Although medical spas have been in existence since ancient times to treat a wide variety of ailments such as gout, arthritis, and diabetes, our modern concept of the medical spa combines relaxation with medical rejuvenative procedures....

journal_title：Dermatologic clinics

authors： Goldman MP

更新日期：2008-07-01 00:00:00

abstract：:"Telemedicine" is defined as the use of telecommunication technologies for the exchange of medical information across distances. Applications include patient management as well as research and education. Teledermatology is a steadily growing category of telemedicine. This article presents general aspects of telemedici...

journal_title：Dermatologic clinics

authors： Wurm EM,Campbell TM,Soyer HP

更新日期：2008-04-01 00:00:00